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In order to confirm the preference of Ag sitting on top of C atoms rather than at the bridge or in the hollow sites (see Figure 4 center) of the C hexagon, an ab initio study was necessary.
CGMD simulations of bilayer self-assembly confirm the preference for the TM orientation.
As well as substantiating the importance of Gly or Ala at the P2 subsite, our results confirm the preference for acidic residues, Ser or Thr on the prime side of the scissile bond and allow us to confidently add Thr to the list of resides that can be accommodated at P4.
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The performance evaluation of the proposed algorithm and the marker algorithms confirmed the preference of the OtswTCM algorithm over the other algorithms.
Crystallographic studies of the unsubstituted spiro-thiazolidinone and the above most efficient inhibitors in complex with RMGPb confirmed the preference and inhibitory effect that aromatic (and especially 2-naphthyl) derivatives show for the catalytic site promoting the inactive conformation of the enzyme.
We independently confirmed the preference of S2 cells for white over opaque cells by presenting the S2 cells with mixed populations of white and opaque C. albicans cells.
Studying the URA3 genotype in greater detail confirmed the preference of uptake over self-synthesis.
This analysis confirmed the preference for Te that was observed in many individual neurons.
Metabolite ratios were similar in a separate experiment using a more pharmacologically relevant CB1954 concentration (10 μ M), which confirmed the preference of NfsA for the reduction of the 2-NO2 group (data not shown).
Other phosphoester substrates were tested and confirmed the preference of MptpB and Lmo1800 for the p-Tyr amino acid over p-Ser and p-Thr and showed modest activity for 5'AMP and 5'IMP (Table 2).
No citrullination was observed after incubation of PPAD with a fibrinogen peptide containing internal arginines, confirming the preference of PPAD for citrullinating peptides with C-terminal arginines (data not shown).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com