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Of note, this particular peptide also contains epitopes of two broadly neutralizing HIV-1 antibodies (2F5 and 4E10) that have been shown to be polyspecific autoantibodies reactive to phospolipid cardiolipin [52] Thus our inability to confirm responses to this particular peptide in HIV-infected subjects may be in part due to its autoimmune nature.
A detailed symptom list and physical examination findings were recorded, and these two forms were used to confirm responses.
Although WHO response criteria were used, it was not possible to confirm responses after 1 month because of resource limitations.
e) section B of the questionnaire with its open-ended structure, clearly does not have the same psychometric properties, but can be used in conjunction with section A to confirm responses regarding the participant's training needs.
Twenty-five structuredtured in-depth interviews were conducted with the 22 "at risk" women between April and February 2010; in 3 cases, the interviews were repeated to confirm responses given by them to the concept and questions discussed during interviews; this was to make sure that their responses were in line with the concept that had emerged based on their responses.
We had originally hoped to compare or confirm responses from publication professionals with those from journal editors and academic investigators, however, we were less successful in promoting the survey among these groups than among publication professionals and consider the response from these sectors too small to be reliable.
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Falling CA 125 levels after treatment are used to confirm response to specific treatments [8] and elevating CA 125 levels signal recurrence [9].
Imaging studies were repeated to confirm response at least 4 weeks (for complete or partial responses) after first documenting a given response.
Tumour dimensions were assessed by CT scanning or MRI every month to confirm response, and after RECIST efficacy was confirmed, every 2 months subsequently.
We did not measure antibody levels to confirm response to PPV-23; however, infection rates are likely of greater clinical value.
Results: In 27% (9/34) a discrepancy was found between the WHO and RECIST response evaluation 9% (3/34) concerned best responses and 18% (6/34) objective confirmed responses.
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