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Falling CA 125 levels after treatment are used to confirm response to specific treatments [8] and elevating CA 125 levels signal recurrence [9].
It has to be noted that the study did not stipulate a further scan 4 weeks later (i.e. 8 weeks post-treatment) to confirm response in responding patients.
Tumour dimensions were assessed by CT scanning or MRI every month to confirm response, and after RECIST efficacy was confirmed, every 2 months subsequently.
The focus group discussions helped us to confirm response options for our items and determine the scale endpoints from no disease to severe CLD.
Imaging studies were repeated to confirm response at least 4 weeks (for complete or partial responses) after first documenting a given response.
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Although WHO response criteria were used, it was not possible to confirm responses after 1 month because of resource limitations.
A detailed symptom list and physical examination findings were recorded, and these two forms were used to confirm responses.
In addition, the IDS-SR30 and QIDS-SR16 confirmed response and remission rates obtained using the HDRS24.
In the GIST group, no patients had a confirmed response and recruitment was discontinued at the first step.
The confirmed response rate was 19%, and median overall survival was 6 months.
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