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To further confirm if Btd is required for ectopic PntP1 to induce the generation of INP-like cells, we then examined if the generation of INP-like cells induced by ectopic PntP1 expression would be impaired in the absence of Btd.
To further confirm if mitochondrial superoxide was required for these Berberine-induced effects, we created BAEC without functional mitochondria (ρ° cells).
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Analytical methods are required to confirm if foods are gluten-free, but current immunoassay-based methods can unreliable and proteomic methods offer an alternative but require comprehensive and well annotated sequence databases which are lacking for gluten.
Additional studies are required to confirm if this change in population is exclusively a nano- effect.
Future investigations using a whole-plant assay are required to confirm if L. leucocephala leachate has similar effects on intact water hyacinth plants under more natural conditions.
However, further research using a larger patient cohort is required to confirm if our findings are representative of the wider CHD population.
In our opinion, this is the first report that significantly associates MAP infection with MS. Further studies will be required to confirm if MAP could be one of the triggers of MS, according to the molecular mimicry theory, in susceptible (and genetically at risk) individuals.
Further analytical studies are required to confirm if the interaction between smoking and alcohol and injury risk exists.
Further studies, with larger sample sizes, are required to confirm if any cardioprotective benefit of total joint arthroplasty varies by the joint being replaced.
Further study would be required to confirm if indeed the timing and duration of milk ejections are actually affected by stress.
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