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Historically, sovereignty has been the golden rule that must not be violated, regardless of what actions take place within the confines of a given territory.
Within the confines of a given metaphor, we distinguish pretty readily between words and phrases that are to be taken metaphorically and others that are to be taken only literally.
Additionally, ontological associations of hub genes can be extended to a neighboring highly connected gene cluster comprising coexpressed genes, within the confines of a given module.
Indeed, cell fate choice of progenitor cells is determined by a combination of intrinsic genetic programs, which define the differentiation potential or the competence state of progenitors, and extrinsic cues, which influence the relative proportions of each cell type generated within the confines of a given competent state (Livesey and Cepko, 2001).
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This stability notion, referred to as Bi-Quadratic Stability, is appropriate to deal with real parameters with magnitude and rate of change which are confined to a given convex region.
But I follow the evidence where it leads, and refuse to be held hostage by the confines of any given political pigeonhole.
We suspect though that within the biological confines of any given cell, the bulk of the p63 functional activity is driven by the major α isoform, while the minor isoforms perhaps represent the misfiring or over-activity of the splicing machinery.
However, its binding does not appear to be sequence-specific, as CENP-A is confined to just a portion of a given multi-mega base array.
Still, my students and peers see themselves as limited to only the confines of the tasks given them — as lacking discretion.
This study was conducted within the confines of clinical reality, given all the usual challenges of staff shortages and sickness; no additional nursing services were provided.
It doesn't help that the nearshore is miles away from the former dams and outside the confines of the park, giving it a somewhat marginal status.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com