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We also investigated switching between a freely diffusing mode and a confined diffusion.
We observed a significant reduction in the proportion of Brownian diffusing HCVpp and an increased number of particles with mixed or confined diffusion on non-polarized HepG2 expressing CD81ΔC compared to wild-type protein (Fig. 8A, Table 1).
For each identified segment, the MSD curve was linearly fitted (Brownian) or adjusted with a quadratic curve (4Dt + νt) (directed diffusion) or exponential curve L2/3 1-exp(−12Dt/L2/3 1-expned diffusion), where L is the side of a square domain, the confinement diameter being related to L by dconf = (2/√π)L).
Confined diffusion of membrane receptors and lipids can result from intramembrane barriers, skeletal interactions, rafts, and other phenomena.
Confined diffusion of membrane proteins is likely a general phenomenon suitable for noninvasive V(r) analysis of force-producing mechanisms.
Single-particle tracking with different fluorescent proteins revealed that the telomere movement is confined diffusion (Fig. S1A and Movies S4, S5 and S6).
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The sulfur AB composite, which can effectively confine the diffusion of dissolved polysulfides in organic electrolyte and stabilize the structure during the charge and discharge process, showed high capacity and good cycle performance.
We performed simulations of fast diffusing particles with a probability to engage into a slower diffusion confined in a trap.
This procedure is validated in the case of high swirled confined natural gas diffusion flames.
Cyclic voltammetric (CV) analysis revealed the linear relationship between the anodic peak current and the scan rate, indicating a surface-confined diffusion process.
Sbalzarini et al. [40], [41] modeled molecular mobility in the ER as examined with FRAP, and compared the outcome with non-confined diffusion.
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