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Furthermore, these spatiotemporally confined abnormalities corresponded to different stages of the semantic decision task and correlated with clinical behavioural measures of cognitive functions.
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For patients, 82.5 % had somatosensory abnormalities in the painful facial region, while 60.0 % had abnormalities confined to the right hand.
This process can lead to a loss of normal prostate functioning, characterized by excessive cell proliferation, inflammatory cell infiltration, and a loss of apoptosis, which in essence is a form of 'remodeling' that can permanently alter the prostate 'architecture.' Although BPH is largely confined to prostate abnormalities, a number of secondary degenerative changes can take place in the bladder.
Recent investigations in a fully genetically characterized cohort of XLI patients and genetic abnormalities confined to the STS gene indicate that testicular maldescent is rare.
PCD related chromosome abnormalities were confined to whole BM while non-PCD related abnormalities were found in both whole BM and NF.
The lesions were also diagnosed as cancer based on obvious cytological abnormalities of the squamous epithelium, even when the abnormalities were confined to the lower half of the squamous epithelium [ 29].
In five of these patients, the abnormality was confined to the precentral gyrus.
In refractory TLE (rTLE) gray (GM) and white (WM) matter abnormalities are not confined to the hippocampus but also are found in extrahippocampal structures [ 3].
Therefore, in parallel, gene expression signature confined to regions with chromosomal abnormalities will be tested as predictors for response to panitumumab in the postoperative EORTC 22071-24071 clinical trial.
The importance of placenta genetics and epigenetics is supported by the observation of increased stillbirth and pregnancy loss in confined placental mosaicism where genetic abnormalities are only present in the placenta [ 11].
Mice that are either hypomorphic for Atg16l1 or deficient in either Atg5 or Atg7 in the intestine display severe cellular abnormalities that are confined to intestinal Paneth cells and resemble the changes seen in CD patients that carry the ATG16L1 risk allele (83, 84).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com