For the sake of clarity, Table 6 summarizes the main successful configuration reported by GA execution.
In order to match the heat transfer surface of the FP (2 m2/mtrench), 10.15 coils have been considered for unit length of trench, split on two levels as a standard configuration reported in [10]; thus, every metre of FP is equivalent to 31.87 m of DN20 slinky-coil.
The results corresponds to a ∼180 degrees rotation of TM2 about the helix axis relative to the configuration reported in ref. [11].
Given this scenario and the parameter configuration reported in Supplementary Table S1, different TS profiles have been simulated with the mlxR package in R (Supplementary Figure S1).
In this study, we conducted a sensitivity analysis across different genetic configurations to evaluate the stability of an automated genetic framework and to discover which genetic configurations report best performance.
The results for the configurations reported here represent both non-swirling "linear" flow and swirling flow.
Finally, we applied a sensitivity analysis with the objective to find which genetic configurations reported best performance.
Bioreactor configurations reported in recent research papers and patents are tabulated, together with their key characteristics, performances, pros and cons.
Numerical results demonstrate that, these two configurations of highly conductive pathways, remarkably surpass the latest configurations reported in the literature, with the same amount of high conductivity materials.
We investigated the results of the best learning schemes performance, compared our genetic framework results with an exhaustive framework (baseline), and conducted a sensitivity analysis with the objective to find which genetic configurations reported best performance.
