Sentence examples for configuration of gene expression from inspiring English sources

Assuming steady state dynamics would collapse the trajectories representing these shifts into a single attractor point at the final configuration of gene expression.

Our model performs significantly better with data from the true distribution, suggesting that our predictions are due to the specific configuration of gene expression and the metabolites that we are testing and not due to a global trend in the expression data.

To identify the attractors of each model, we used the program Atalia [[ 56]; freely available] by following the dynamics of all possible initial configurations of gene expression.

Predictive models recognize numerous chromatin "states" presumably indicating regulatory elements, gene activity, and other aspects of genome biology [ 3, 4], thereby deducing chromatin configuration from our knowledge of gene expression and chromatin marks.

Histone deacetylases (HDACs) are important class of enzymes that deacetylate the ε-amino group of the lysine residues in the histone tails to form a closed chromatin configuration resulting in the regulation of gene expression.

The presence of a strong attractor-like structure constraining the genome-wide expression at the cell population level into a very sharply defined configuration spanning the entire set of gene expression values allows for only minor departures from unit of the autocorrelation in time.

In both the repressor and activator configurations, we have demonstrated tight control of gene expression both in transient and stable expression.

This configuration has been suggested in the analysis of gene expression data [ 14] although more components can be considered to improve the data fitting.

Although the reverse mutant is sub-optimal, we have combined two configurations of the switch to generate tight control of gene expression.

In the latter configuration the cell would rely on MAP3K11 to bypass the inhibitory effect of AKT1 on AP1-mediated regulation of gene expression.

The role of transposon transcripts in the regulation of gene expression was recently discovered in yeast [ 35], where the induction of an RNAi-dependent silent chromatin configuration resulted in reduced transcription of several meiotic genes.