Sentence examples for configuration of binding from inspiring English sources

As discussed above, though, these conclusions are based on the assumption that the measured increase in the ChIP signal for Est1 and Est2 reflects an increase in association with the telomeric target site, rather than increased catalytic activity of a change in the precise molecular configuration of binding.

We postulated that by using an inactive mutant CTB protein as the scaffold, once modified with carbohydrates, the resulting pentavalent ligand should provide a precise fit of the ligand groups with the spacing and configuration of binding sites on wild-type CTB.

Fig. 4 Network view - configuration of bindings and routes for Infrastructure Hitch Hiker.

Although examples of association between BRG1 and TFs have been previously described (Trotter and Archer, 2008; Reisman et al., 2009; Euskirchen et al., 2011), this specific configuration of BRG1 binding to nucleosomes flanking the TF binding sites has not been generally recognised.

Since D100A is located in the binding pocket of the 5-HT4 recepthis this mutation in Rs1 may have changed the configuration of the binding pocket, making the receptor more susceptible to Gq activation by zacopride and RS23597.

The configuration of this binding site is unexpected.

The selection among these mechanisms appears to be at least partly dependent on the sequence and configuration of Rap1 binding sites (Piña et al. 2003).

The conserved intron insertion site, G307, seemed to be an especially important hinge region by which the working angle could be used to adapt to the global configuration of the binding surface.

In addition to examining the configuration of consensus binding sequences among gene clusters (FCS P value), and calculating their hypergeometric enrichment P values within each cluster, we also used MDscan [ 56] to identify overrepresented sequences in each of the gene clusters that may not be included in our TFM list.

Therefore we speculate even both sites (p53-BS1 and p53-BS2) have conserved CATG sequence domain, but only p53-BS1 binds to p53 protein and inhibited Malat1 gene activation, hence the background sequence of p53-BS1 with conserved domain CATG may favor a configuration of p53 binding.

It inferred that these two residues are essential for their common configuration of substrate-binding pockets.