Sentence examples for configuration of alcohol from inspiring English sources
It is worth noting that configuration of alcohol 25 is opposite to the alcohol 23 despite the fact that stereochemistry of carbon atom C-4 is the same in both substrates.
Whereas the H-4 H-3 coupling constant in 20, wH-4 H-3iginated from the alcouplingth the R constantatinn, was 1.0 Hz, a value of 3.7 Hz was measured for cyclic intermediate 18, and thus, the stereochemical configuration of alcohol 13 could be confirmed.
They were investigated by H NMR spectroscopy (400 MHz, CDCl3) to determine their de, which corresponded to the ee of the underlying [D1] 4, and the configuration of the alcohol obtained by coupling.
[21] The reaction of compound 4 with (R, S -α-methoxy-α- trifluoromethyl phenylacetyl (MTPA) chloride in pyridine formed (S -α-methoxy-α- trifluoromethyl phenylacetyling valueS -α-methoxy-α- trifluoromethyl phenylacetylativeS -α-methoxy-α- trifluoromethyl phenylacetylry alcohol of 4 waS -α-methoxy-α- trifluoromethyl phenylacetyl8).
This suggests that although subunit configuration may affect regulation of alcohol responsivity, other factors also are involved, consistent with the findings by other researchers (Jin and Woodward 2006; Woodward 2000; Xu and Woodward 2006; Xu et al. 2008).
Moreover, the consistency in the signs of ΔδF (δR �� δS) values suggests that the FICA method would be reliable in assigning the absolute configurations of secondary alcohols based on 19F NMR spectroscopy.
The absolute configuration of the recovered chiral acetylenic alcohol 3 was determined to be R by the modified Mosher ester [18] (Additional file 1).
