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This strip in the rectangle is further referred to as the confidence strip (Fig. 2d).
Expected D e, e′) and Density D e, e′) are defined using the same formulas and the corresponding confidence strip.
We also define Points e, e′) as the total number of read-pairs (from the real dataset) that correspond to the points within the confidence strip.
The points outside the confidence strip may represent read-pairs with somewhat larger deviations from the mean insert sizes or chimeric read-pairs.
Let F x) be the empirical distribution of the insert size and S be a set of all integer points within the confidence strip in the rectangle (e, e′).
When (e1, e2) is a false edge-pair, D* defines a confidence strip S t r i p D * (e 1, e 2 ) with the maximum number of chimeric read-pairs.
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