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If, with a high confidence prediction, the predicted link-label disagrees with the actual label then this may indicate an outlier (a wrong link-label) and the datapoint should not be learnt.
16 17 A 2013 Japanese study demonstrated an overall sensitivity and negative predictive value for high confidence prediction of deep malignant submucosal invasion of 92% in a tertiary centre setting.
Intraobserver agreement was achieved in 113 out of 121 polyps (93.4 %), leading to an almost perfect κ coefficient of agreement of 0.867 [95 % CI: 0.799 0.967].> -wrap-foot> Confidencence Interval, PPV Positive Predictive Value, NPV Negative Predictive Value, HC High Confidence High confidence prediction of histology was made in 107 of 121 polyps (88.4 %).
The measured performance and uncertainty analysis indicated that the ANN-m was the best performing model with R2 (0.97), RAE (0.21), D (0.93) and the lowest 95% confidence prediction error interval (+0.22 to +3.49).
He upheld his prediction in an interview with Yahoo's Tech Ticker, arguing that, with the government's stimulus package, "the problems haven't been solved, but they've been postponed". Faber added that he has a "high confidence prediction" that "total collapse will come". Yikes.
If a putative novel miRNA fulfilled all of the above, we denoted the novel miRNA as representing a "high confidence" prediction.
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Of the 17,781 predicted interactions, there are 3,143 high-confidence predictions (predicted by ME [ 40] or at least two different approaches), 729 medium-confidence predictions (hetero-domain interactions in which both domains have the same annotations in the biological process of the gene ontology), and 13,909 remaining low-confidence predictions [ 23].
Schiffer, A.-M., Boldt, A., Waszak, F. & Yeung, N. Confidence predictions affect performance confidence and neural preparation in perception decision-making.
Nguyen, A., Yosinski, J., & Clune, J. Deep neural networks are easily fooled: High confidence predictions for unrecognizable images.
Moreover, the flexibility built into the DIOPT graphical user interface allows researchers with different goals to appropriately 'cast a wide net' or limit results to highest confidence predictions.
Taking the intersection of the sets of miRNAs found to associate positively with the two previously validated hypoxia gene signatures (Hypoxia, Buffa et al.24 and Hypoxia, MSigDb25), we obtained high confidence predictions for hypoxia-associated miRNAs.
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