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Thus we used both a different annotation pipeline and a different confidence classification system.
According to the confidence classification rules described in (32), these interactions can be classified into high-confidence, medium-confidence and low-confidence.
Possible reasons for this are: i) the much shorter V6 lengths; ii) that its hyper-variable and poorly conserved sequence impedes high-confidence classifications; and/or iii) that it is flanked on both sides with highly conserved sequences which add little classification information.
Section 2 introduces the flow of the proposed fusion strategy, the definition of classification confidence and classification weight in each level.
For any given image located in Clinical Face Phenotype Space, we obtain confidence ranked classifications to known disorders (see 'Materials and methods' and Figure 4 figure supplement 4).
Highest confidence relationship classifications were those for which all methods were congruent, rendering our approach conservative in order to minimize error introduced by limitations in sampling (absence of parental data) and the limited power of our set of genetic markers for distinguishing adjacent relationship categories.
The class value of an instance is determined based on the classifier with the maximum classification confidence, where the classification value of an instance is its signed distance from the SVM hyperplane.
However, inconsistent diagnostic terminology [ 12], lack of universally accepted diagnostic classification criteria [ 13, 14] and poor specificity of many physical examination tests [ 15] hamper confidence in classification systems that use clinical test criteria alone.
Thus, the confidence of classification will be improved.
Across varied test stimuli, confidence-based classifications equalled or out-performed single decisions.
Different applicability domain (AD) approaches were used to estimate the confidence of classification.
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