Sentence examples for confidence alignment from inspiring English sources

If alignment length is identical then the highest confidence alignment is selected.

Furthermore, the Brown dataset used in my original report had ambiguously aligned regions removed [ 103], including all indels, essentially eliminating any potential alignment bias and resulting in a very high confidence alignment.

However, automated sequence alignment is unreliable at high divergence levels, so we excluded orthologous pairs with less than 30% identity (leaving 4,975 contigs) to avoid false mismatches introduced by low confidence alignments.

We note that our analysis probably has a strong bias toward detecting conserved sequences, since we limited our analysis to high confidence alignments and thus probably excluded highly diverged orthologous pairs.

This threshold is considerably higher than the standard required for genomic sequencing but provides reasonable sequence coverage for gene with nonuniform transcript coverage, In addition, the alignment parameters for Bowtie resulted high confidence alignments and minimize alignments containing insertions or deletion.

Since highly repetitive/low complexity genomic regions may result in ambiguous or low confidence alignments, we conservatively filtered out all alignments with mapping quality (MAPQ) < 35.

To focus on high-confidence alignments, we conservatively selected those having 10 or more overlapping SOLiD small RNA reads aligned with a single genomic location.

We show that composite Illumina reads from high-confidence alignments perform at least as well as reads obtained from 454-FLX.

Between 449,113 and 946,110, high-confidence alignments were obtained for each sample (Supplementary file 2).

In the control experiments containing just three Dscam1 isoforms, only 642 of 50,475 high-confidence alignments (1.3%) contained ligamers for exons not present in any input transcript, with the majority of these species (221/236) represented by three or fewer reads.

We aligned the read sequences from each experiment to the hg19 reference genome, standardizing the read length and removing low-confidence alignments in order to ensure accurate mapping without read-length bias.