Sentence examples for conferring regulation from inspiring English sources

Given that the Nis promoter region conferring regulation by Pax8 (NIS upstream enhancer) overlapped with potential sites for both transcription regulators (data not shown), we performed transfection experiments in HeLa cells using a reporter construct containing the Nis promoter [ 17].

The classical PKC isoforms, contain domains conferring regulation to diacylglycerol and Ca2+ and require both for full activation.

Iron sulfur clusters [Fe-S] are present in the active sites of many enzymes and proteins, critical for their activity and capable of conferring regulation by redox status [21].

Likewise, also GM-CSF reprograms monocytes into anti-inflammatory cells but with different features to confer regulation of inflammatory response.

Indeed, a perfect complementary between miRNA and target site was even shown to be entirely unable to confer regulation [6].

For this group, a 3'-UTR motif with a consensus sequence [UUGUACC] seems to be necessary but not sufficient to confer regulation.

Furthermore, large-scale miRNA mis-expression studies also have suggested that seeds in coding regions can confer regulation but are on average less effective than those in 3'UTRs [7], [7].

It has been reported before, that two lacO sites positioned on either site of the transcription start site are sufficient to confer regulation to mammalian promoters by lacI and IPTG, while the third binding side is usually positioned further up or downstream and mainly serves to increase the local concentration of lacI [11].

However, although their work revealed two additional short regions in close proximity to the analyzed target site of the miRNA lys-6 in C.elegans, all of these features together showed to be not sufficient to confer regulation in UTRs of other worm genes.

Several studies have provided evidence that seed matches in the coding sequence and 5'-UTR can also confer regulation by a miRNA, as judged by mRNA expression data, Ago2 IPs in Drosophila, phylogenetic conservation analyses and reporter studies [6], [43], [50], [53] [55].

While the presence of a binding element does not confer regulation, MSI1 regulation of lipid metabolism may be more complex than simple direct regulation of SCD.