High-level association cortices not only receive feedforward signals from sensory regions but also anticipate and reciprocate these inputs with backward connections conferring context-specificity and higher-level constraints (i.e. predictions) (Rao and Ballard, 1999; Friston, 2003, 2005; Angelucci and Bressloff, 2006).
One important caveat against these rather simple models of tumourigenesis, is the capacity of genes to confer context dependent effects on stem cells.
Together with previous evidence, our study indicates that ChiLS confers context-dependence on TCF/LEF by integrating multiple inputs from lineage and signal-responsive factors, including enhanceosome switch-off by Notch.
A broader examination of the properties of a series of fully parameterized models both for independent and overlapping-tuple cases has also been done [ 16], demonstrating a substantial improvement in fit conferred by context dependent models over independent nucleotide models.
However, the people who participated in the consultation were experts in HIV-prevention interventions among the target populations in this geographical and cultural context, thereby conferring credibility to the findings.
The enediyne self-sacrifice genes and corresponding encoded proteins have been validated in the context of conferring enediyne resistance, but it remains possible that such proteins or their proteolytic fragments could also serve alternative roles in Micromonospora.
Systemic proinflammatory context confers resistance to malaria infection in mice [150], [151], [152] and correlates strongly with human resistance [153], [154], [155].
Implementation in this context confers challenges in terms of technological infrastructure, privacy and regulatory issues.
Our new findings shed light on the role of RhoB in tumorigenesis involving a dual effect conferred by cellular context with a potential pro-oncogenic function in hormone-dependent breast cancer cells.
So our imaging ability on those women is not as good and their expectations are not less.' (Participant no 2) The obstetricians believed that many women were unaware of what problems overweight and obesity could confer in the context of obstetric ultrasound examinations.
