The proposed scheme produces grids that combine the benefits of an unstructured mesh with the structure conferred by the underlying spherical spiral.
However, it may indicate that bilateral disease in the context of familial testicular cancer has a different pathogenesis from sporadic bilateral cases and that most of the familial bilateral cases are explained by the elevated risk conferred by the underlying susceptibility genes.
From the currently available data, it is impossible to judge which of the associated FTO sequence variants might confer the molecular effects underlying these genetic findings.
Convergent epidemiological and laboratory data have suggested that A2A blockade may confer neuroprotection against the underlying dopaminergic neuron degeneration.
Typically, an exceptional retention of paralogs is a consequence of a newly gained function which may confer additional fitness and prevents the underlying gene from being weeded out again (Dittmar and Liberles 2010; Chain et al. 2011; Sikosek et al. 2012).
Identifying the underlying genes conferring MD genetic resistance is desired for more efficacious control measures including genomic selection, which requires accurately identified genetic markers throughout the chicken genome.
This form of analysis is therefore a useful tool to elucidate the complex epigenetic code associated with genome function and to determine the underlying features conferring epigenetic states.
This long tail suggests that the underlying mechanism conferring the risk must persist for a considerable period of time, and possibly for long after the resolution of clinically apparent morbidity.
In order to fully elucidate the underlying mechanisms conferring pyrethroid resistance in a resistant strain of the major malaria vector A. funestus, we successfully carried out a fine-scale mapping of the rp2 QTL associated with this resistance.
However, the underlying mechanisms that confer their antimetastatic and apoptosis-inducing abilities were uncertain.
To date, the results have been disappointing, perhaps because of a lack of understanding of the underlying mechanisms that confer resistance to immunologically based therapies.
