Sentence examples for confer the strongest from inspiring English sources

Haplotypes carrying the HLA-Cw*0602 HLA-Cw*0602er the strongest genetic effect in whites, pallelelarly among early onset confer(8, 9).

Although variants in TCF7L2 confer the strongest risk of T2D among common variants by presumed effects on islet function, the molecular mechanisms are not yet well understood.

For example, the eight mutants that confer the strongest defects in Spt16−gene interactions (H3-L61I, Y, E, H, V, T, K, and W) are also the ones that show the most robust growth on SC-his GAL plates.

Among known predisposition genes, deleterious mutations in BRCA1 and BRCA2 confer the strongest effect on disease susceptibility and are associated with a lifetime risk of breast cancer of up to 85% for such mutation carriers [ 4, 5].

Wild alleles confer the strongest known resistance phenotypes not only against rust (Varshney et al. 2014) but also late leaf spot (Khedikar et al. 2010) and root-knot nematode (Stalker et al. 2002; Simpson et al. 2003; Chu et al. 2011; Burow et al. 2014).

However, human leukocyte antigen (HLA) loci, and in particular selected HLA class II DR and DQ alleles, confer the strongest risk being associated with ∼40%% of T1D cases, clearly indicating that susceptibility for the disease is at least partially inherited [ 4].

These results indicate that egl-8 mutations confer the strong suppression for the synaptic defects in ttx-7 mutants.

Each of the Hsp104 variants tested slightly suppressed the toxicity of α-synWT, and Hsp104A503S, Hsp104V426L and Hsp104Y507C conferred the strongest rescue (Fig. 3B).

The same was observed in the presence of Ten1 (Fig 4, compare row 6 with 11 and 3): the SUMO-Tpz1(243–420) construct in the presence of Ten1 conferred the strongest observed growth in the Stn1 interaction assays.

It is worth noting that FLCLov-5 confers the strongest effects among our populations, especially in the P2 population with a measured effect of 11.5 days for the trait DTF1.

Mutation of the two highly conserved Z-boxes showed that Z-box 2 confers the strongest repressive function by ZEB1 (Fig 2B, right) and also made the promoter activity insensitive to stable knockdown of ZEB1 (supplementary Fig 1D online).