All five vectors carry a mutated downstream stretch of the sdi1 sequence, carrying a carboxin resistance-conferring point mutation (H267L; Fig. 2A, left flank), and a sequence stretch downstream of sdi1 (Fig. 2A, right flank of sdi1).
To test for this, we created missense mutations in the Maf1 portion of the fusion construct, utilizing previously characterized maf1 alleles maf1-1044 and maf1-124) conferring point mutations that resist dephosphorylation (Roberts et al, 2006).
Targeted integration into the genomic sdi1 locus of Z. tritici is achieved by a mutated downstream stretch of the sdi1 sequence, carrying a carboxin resistance conferring point mutation (H267L; Fig. 2C and D, left flank), and a sequence stretch downstream of sdi1 (Fig. 2C and 2D, right flank of sdi1).
WANTS BANKERS TO CONFER He Points to the Agreement Made With Them During Harding Administration.
California's best high schools offer so many A.P. and honors classes — which confer bonus points on a student's G.P.A. — that the average G.P.A. of white and Asian freshmen at U.C.L.A. is now 4.2.
An example of comorbid illnesses is the diagnosis of cancer, which confers two points, whereas an example of a functional impairment is the inability to bathe oneself, conferring two points.
It was a scaled down test, and still a far cry from a pod capable of actually transporting humans, but it's a sign that the 120-strong team of engineering students is on the right track (hope someone is conferring bonus points on me for puns, too).
The presence of each disease was given 1 point while a prior cerebrovascular accident (CVA), defined as ischemic stroke or TIA, conferred 2 points.
De novo resistance may not be irrelevant for all antimalarials, and where single point mutations confer high level resistance as, for example against atovaquone (White 2004), de novo mutations may be a serious issue clinically.
This can be conferred by point mutations or gene amplification events.
Not found in other kinases or the small number of mammalian HKs, the Bergerat fold confers a point of selectively among abundant eukaryotic proteins.
