Sentence examples for confer interaction from inspiring English sources

Computational approaches such as docking confer interaction of small molecules with structural macromolecules and thereby hit identification and lead optimization.

This includes a 'PxVxL' motif (PKVVL at position 480), which has been shown to confer interaction with HP1α in numerous proteins [29].

The SUV420H2 protein contains a related PHCRL sequence at position 364 that is present within a short region of the protein known to confer interaction with HP1α and localization to PCH [10], [27], [28].

XpsD in different strains could direct the secretion of different sets of proteins adapted for function in different tissues, or, as a bacterial outer membrane protein, XpsD could function as an elicitor of tissue-specific plant responses that confer interaction specificity.

Notably, Map1p contains two zinc-finger motifs, one CCCC-type and the other of the CCHH-type [33], which occur in DNA-binding proteins and in some RBPs [34] – however these domains were not thought to provide selective RNA-binding but rather to confer interaction of Map1p with the ribosome [35].

Although neither the crystal nor solution structure is known for any of the E1A proteins, mutational analysis has clearly shown that the E1A proteins are organised as a collection of independent protein-binding modules that confer interaction with a number of cellular proteins (Gallimore and Turnell, 2001; Frisch and Mymryk, 2002; Berk, 2005).

The scaffolding region of the degradosome, namely the C-terminal region of RNase E, is also highly flexible, and this would help to confer interactions and cooperation between degradosome components.

Although the zipper region also exhibits variability, multiple mutation studies have found that it confers interaction preferences and is essential for dimerization (Reddy et al. 1992; Arsura et al. 1995; Orian et al. 2003).

For instance, multiple independent sterility-conferring interactions may exist: alleles at loci A and B can interact to cause sterility, and a separate interaction between loci C and D may also be sufficient.

Genetically, this tail is crucial for c-Abl function, and mice homozygous for a C-terminally truncated c-Abl (ablm1 mice) share most of the phenotypic defects of c-Abl null mice.15,16 This region contains three PxxP motifs, conferring interactions with SH3 containing proteins.

The structure of G9A reveals that histone H3 lysine 4 is buried in an acidic fold comprising the aspartic acids D1074 and D1088, suggesting that the aspartic acid residues would confer electrostatic interactions with the positively charged H3K4 and that methylation of H3K4 could interfere with those interactions.