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All these variants only confer a small to moderate change in risk for migraine, which concurs with migraine being a heterogeneous disorder.
The use of these labels may be avoided by setting criteria F to '1', and may confer a small performance advantage as a result.
We have proposed a model in which genes that confer a small risk for psychosis interact with neurodegenerative illness to yield manifest psychotic symptoms during AD.
This is important since polygenic multifactorial diseases are likely caused by many alleles that confer a small individual effect but a high risk in combination.
Among the 117 primary studies in humans, 74 articles state in their summary that alleles of the DRD4 genes are significantly associated with ADHD but only 19 summaries also mentioned that they confer a small risk.
Interestingly, though platensimycin had a minimal effect on FabH of other bacteria [2], overexpression of Mt-FabH in theory should confer a small degree of resistance to platensimycin but no significant change was observed (Table 1).
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However, it could be that SNPs in the FCER1A gene region confer a smaller risk of developing AR.
In contrast, a weak repressive MRE would confer a smaller selection advantage because of the limited effect of splicing-mediated protein suppression by microRNA.
Variants found in this class of genes confer a smaller risk of breast cancer than BRCA1/2 and, because of their rarity, are very difficult to detect in the population.
The new study found four DNA regions that conferred a small risk of psychiatric disorders.
The common diseases, which the company will assess, are generally caused by several different mutations, each one of which confers a small extra risk.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com