Sentence examples for confer a high risk from inspiring English sources

Generally, BRCA1 variants are sorted into three categories2,3: benign variants, which cause no concern; deleterious variants, which can confer a high risk of cancer; and an unsettling intermediate known as variants of uncertain significance (VUS).

Critical illness encompasses a diverse group of diseases that confer a high risk of both mortality and morbidity [1, 2].

RAS mutations are common in thyroid tumors and confer a high risk of cancer when detected in fine-needle aspiration (FNA) specimens.

Interestingly, monoallelic mutations in some of the downstream proteins are known to confer a high risk of breast cancer (e.g., FANCD1 = BRCA2, FANCN = PALPB2, FANCJ = BRIP1, FANCO = RAD51C).

Deleterious germline mutations in BRCA2 are rare but confer a high risk of breast cancer.

For case-control studies, controls selected from hospital populations was considered to confer a high risk of bias.

Persistent marijuana use before adulthood may permanently impair cognitive functioning (Solowij et al, 2002; Meier et al, 2012) and confer a higher risk of developing psychiatric diseases, such as schizophrenia, in susceptible individuals (Arseneault et al, 2004).

Previous studies in cemented stems have found that short stems do not confer a higher risk of peri-prosthetic fracture [10].

The timing of a fever is crucial, however: A fever in the mother can confer a higher risk for the disorder in the unborn child.

BACKGROUND: Depression is 4 to 5 times as common in heart failure (HF) patients as in the general population, might confer a higher risk of developing HF, and negatively affects prognosis in established HF.

Linear GBCAs are thought to confer a higher risk of cerebral deposition, and their use is now discouraged by the EMA [54], although this guidance has not been reciprocated by the FDA [55].