Conduits made of various materials could be tested, so new perspectives for research work at Civil Engineering Institute are new broken open.
We used composite valved conduits made from cryopreserved homograft and polytetrafluoroethylene (PTFE) in 66 cases (54 pulmonary, 12 aortic homografts), other valved conduits in 14, and unvalved PTFE in 8 cases.
We have previously used artificial nerve conduits made from bioresorbable poly-3-hydroxybutyrate (PHB) in order to refine the ways in which peripheral nerves are repaired and reconnected to the target muscles and skin.
Cylindrical nerve conduits made of 80/20 poly (d,l-lactide-co-ε-caprolactone) copolymer were fabricated using an ink-jet system that digitally controlled various manufacturing parameters that ultimately dictate the physical and chemical properties of the scaffold.
Only a portion of Rome's aqueduct system actually crossed over valleys on stone arches (50 km out of a total of about 420 km); the rest consisted of underground conduits made mostly of stone and terra-cotta pipe but also of wood, leather, lead, and bronze.
Although artificial nerve grafts constructed from non-resorbable materials (e.g. conduits made from silicone or polyethylene) have yielded some degree of functional recovery, long-term complications often mean that a second surgical procedure is necessary to remove the conduits.
Multilayer tubular conduits, made of collagen fiber networks and elastin-like protein polymers, characterized by collagen ultrastructure (internal diameters: 1 and 4 mm) and mechanical properties similar to native blood vessels with limited platelet adhesion, were implanted in a rat aortic interposition model.
We have developed a novel synthetic conduit made of poly ε-caprolactone (PCL) that has demonstrated promising peripheral nerve regeneration in short-term studies.
In this study we evaluated effects of biodegradable tubular conduit made from poly-β-hydroxybutyrate (PHB) scaffold with predominantly unidirectional fiber orientation and supplemented with cultured adult Schwann cells on axonal regeneration after cervical spinal cord injury in adult rats.
In this study we investigated the effects of a biodegradable conduit made from trimethylene carbonate and ε-caprolactone (TC) containing poly-p-dioxanone microfilaments (PDO) with longitudinal grooves on regeneration after SCI in adult rats.
