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They regulate the electrical potential of cell membranes and, thus, the conduction of nerve impulses.
Local anesthetic agents work by preventing the conduction of nerve impulses.
Important aspects of biophysics have been derived from physiology, especially in studies involving the conduction of nerve impulses.
Analgesic, any drug that relieves pain selectively without blocking the conduction of nerve impulses, markedly altering sensory perception, or affecting consciousness.
Local anesthetics can block conduction of nerve impulses along all types of nerve fibres, including motor nerve fibres that carry impulses from the brain to the periphery.
This process causes the insulating myelin of axon segments to be lost, and conduction of nerve impulses down the axon is blocked.
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Since the conduction velocity of nerve fibres and pathways is partly dependent upon thickness of the myelin sheath, alterations in the sheath could potentially increase or decrease the synchronicity of brain regions that work together, making them process information more or less efficiently.
The main use of quinidine, however, involves its activity as a myocardial depressant that is, it depresses the excitability and conduction velocity of nerve impulses and the contractility of the heart muscle.
MDC1A patients as well as dy3K/dy3K mice display dysmyelination neuropathy that leads to reduced conduction velocity of nerve impulses [45] [47].
Conduction velocity of nerve fibers varies linearly with the diameter of the fibers.
The conduction velocity of nerve fibers varies linearly with the diameter of fibers [ 7].
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