Nevertheless, by 16 weeks, the speed of conduction in mutants had caught up with and was indistinguishable from controls.
Since desmin is the most abundant protein in these fibers [ 45], the expression of mutant desmin may significantly disturb the cellular function of the cardiac conduction system.
In these animal models, either knock-in of mutant LMNA (dominant negative)[ 17] or knock-out of LMNA (haploinsufficieny) cause DCM in mice [ 16, 18], but variable cardiac phenotypes with or without conduction system disease were observed.
They regulate the electrical potential of cell membranes and, thus, the conduction of nerve impulses.
The speed of conduction of impulses along sensory and motor fibres can be measured with nerve conduction studies (NCS).
Mineralization is also critical for the growth of tendons and ligaments and for conduction of currents in muscles and nerves.
However, there exist several possible algorithms for conduction of ICA.
Christof Bott: Conduction of the study, analysis of behavioural data.
FT participated in clinical conduction of the study.
HK coordinated the conceptualization and conduction of the project.
