However, these former studies were conducted in substantially smaller cohorts and without differentiation of tumour sub-localizations [ 25, 38].
Furthermore, the MTX dose of 6 8 mg/week, although consistent with the dosage commonly administered in Japan at the time the study was conducted, was substantially lower than that commonly administered in Western countries (eg, 15 20 mg/week).
Justice Breyer said suits under the law should be allowed when "the defendant's conduct substantially and adversely affects an important American national interest, and that includes a distinct interest in preventing the United States from becoming a safe harbor (free of civil as well as criminal liability) for a torturer or other common enemy of mankind".
However, perhaps there is another reason why the Langley Large Aerodrome "A" fails to put in an appearance... the notorious 1914 "tests" that Curtiss conducted using a substantially altered, rebuilt and strengthened Langley Large Aerodrome "A" in order to demonstrate that the Wrights weren't the first to fly.
Our results complement and extend previous reports which have been conducted on a substantially smaller scale [ 2, 4].
JG designed the field study, conducted fieldwork, was substantially involved in the design of the statistical analyses and in the discussion of the results, and significantly developed the draft.
The exact prevalence rates of CAM usage in individual far eastern countries is not well known as there have been substantially fewer well conducted population weighted surveys investigating this.
Where there has been a breach of the electoral rules, it is possible to challenge the outcome of an election, but the election will not be declared void if it was "conducted as to be substantially in accordance with the law as to elections" and "the act or omission did not affect its result".
CMC conducted the analyses and substantially contributed to the manuscript.
Trials performed in different regions of the world differ substantially; those conducted in non-high-income countries recruit from a greater number of study sites and study more advanced-phase interventions.
