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They should be adequate in terms of sample size, population, comorbidity, phenotyping and/or genotyping, end-points and outcome measures, and conducted in conditions of dose, route and timing of co-administration that reproduce the proposed therapeutic indications of the new drug.
The election of a pope is conducted in conditions of secrecy unique in the modern world.
In a separate experiment, conducted in conditions of systemic beta-adrenoceptor (atenolol) and muscarinic (atropine) blockade, atrial and ventricular pacing protocols were applied before and after acute bilateral silencing of the DVMN neurons by targeted microinjections of a potent GABAA receptor agonist muscimol.
The measurements conducted in conditions of slow increase of frequency up to 10 Hz in the case of these nanocomposites containing above 1.5 % GO showed nonlinear loss of constants values ε′ and ε″, while these constants in the case of PU without admixtures had values 5 and below 0.1 and changed with frequency insignificantly [ 6].
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Simulations were conducted in conditions that yield varying amounts of accessible volume in the lattice, acting on the density of the system, and introducing geometrical restrictions to motion.
Multiple tests were conducted in various conditions of pressure, temperature, and hydrogen concentration.
The experiment conducted in the conditions of a foreign language course resulted in increased student motivation towards learning.
2. Integration of experiments into routine clinical practice Integration of experiments into routine clinical practice Observational studies and pragmatic clinical trials conducted in the conditions of usual clinical practice are the main methods to conduct comparative effectiveness research and to generate real world evidence.
However, this research is generally conducted in controlled conditions because of the difficulty of manipulating soil communities in the field.
In all these studies, many of which have been conducted in the controlled conditions of the lab, clumps of coöperators thrive and replicate, while selfish groups wither and die.
Therefore, prevention strategies, such as the use of HME devices during training in cold environments, the fixing of appropriate thermal thresholds during competitions conducted in subfreezing conditions and the introduction of stricter regulations on air quality in indoor sportive arenas/swimming pools, should be enforced.
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