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Meta-analyses were conducted for trials comparing VSC with SAC, using the statistical tool Revman 5.1.
7 A meta-analysis was conducted for trials that provided sufficient data to weight the effect size estimates by a function of the reciprocal of the square of the standard error of the effect size estimate.
To explore additional clinical questions pertinent to use of these therapies in rheumatoid arthritis, namely as monotherapy or in MTX-naive patients, separate analyses were conducted for trials of monotherapy in DMARD-IR patients, in which DMARDs were discontinued prior to treatment initiation, and randomized controlled trials in MTX-naive patients.
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Analysis was conducted for all trials as patient randomized, ignoring clustering in the three trials.
A search was conducted for controlled trials using the databases Medline, Embase, SPORT Discus and Cochrane Central Register of Controlled Trials.
In a stratified analysis, trials are grouped according to a particular feature or characteristic and separate meta-analyses are conducted for the trials within each subgroup.
The experiments were conducted for 10 trials.
Searches of Medline using the OVID platform were conducted for treatment trials and other clinical descriptions of affected pediatric populations.
Delivery of PLANS for the BRIGHT trial and Summary of the PLANS support calls conducted for the BRIGHT trial sections elucidate how PLANS was delivered in the trial.
After one month, seedlings with uniform growth were selected and transplanted to experimental plots and general field managements were conducted for all three trials.
Analyses were conducted separately for trials in patients with moderately severe to severe AD, and with mild to moderate AD.
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CEO of Professional Science Editing for Scientists @ prosciediting.com