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A recent comprehensive analysis of DNA binding preferences conducted for a large group of transcription factors revealed that approximately half of these factors recognized multiple distinct sequence motifs, indicating that DNA binding preferences of transcription factors may be more flexible than previously realized [31].
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Data for this paper draws on qualitative interviews conducted for a larger project.
For example, if the exposure is a biomarker, measurements may be prohibitively expensive to conduct for a large study or impossible to conduct because of the lack of appropriate biospecimens available for analysis (for example, lack of prospectively collected or adequately preserved samples for biomarker measurement).
Lack of sufficient focal mechanism data prevents from using the standard Kostrov (1974) method to map the deformation rate, as what has been conducted for a much larger spatial scale by Qin et al. (2002).
In addition, this study is conducted for a much larger number of targets, e.g. several hundreds of cells, while the motions of targets are more strongly correlated than those considered by the previous studies.
It is the largest survey ever conducted for a single terrestrial species and was co-ordinated with the support of the local governments.
In order to acquire the training data for the neural networks (NNs), we conducted experiments for a large number of randomly generated single output Boolean functions (BFs) and derived the simulated graphs for number of min-terms against the BFC for different number of variables.
Two-session SRS conducted for large tumors achieved a durable tumor volume reduction coupled with symptom relief in 6 of 7 cases.
Published after the cut-off date for the searches conducted for this study, a large (over 48 000 patients receiving VKAs only), well-conducted, high-quality observational study reported a major bleeding rate of 1.9 per 100 patient-years in patients treated with VKAs only over an observation period of 2005 2008.
As predicted novel miRNAs only have genomic coordinates and can differ from sample to sample, it would be difficult to conduct comparison for a large number of samples.
The analysis included a comparison with similar evaluations that were conducted for large hydroelectric projects: two hydropower dams on the Mekong River in Thailand, one multipurpose dam in Korea, and the Three Gorges Dam in China.
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