Resources precluded the conduct of the detailed protocol on all RBCT badgers.
The 'Canadian Bandaging Trial Group' members served as site investigators and contributed to the feasibility and conduct of the trial protocol.
During the conduct of the experimental protocol, the KKAy mice were allowed access to high-fat diet (HFD) and water ad libitum.
The 'Canadian Bandaging Trial Group' members served as site investigators, contributed to the feasibility and conduct of the trial protocol, and contributed to the interpretation of the results of the cost-effectiveness analysis.
Because of significant advances in the second-line therapy of mCRC that resulted in the evolution of standard of care during the conduct of the trial, the protocol was later amended to allow the inclusion of patients with up to four prior lines of chemotherapy.
We conduct theoretical analysis of the protocol and study its performance via simulations.
Reasons for low adherence to GDT include time consumption of conducting the protocol, the tendency of monitoring to be invasive and personal disbelief that such a protocol will result in better outcome [ 25].
A small evaluation of the Ion AmpliSeq panel was conducted, although modification of the protocol was required in order to conduct the analysis on the MiSeq instrument.
- A process evaluation will be conducted after implementation of the protocol and inclusion of the first 40 cases treated with the multidisciplinary outpatient care program.
Written consent was obtained from every individual according to the Ethics Committee for the Conduct of Human Research protocol.
