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In the present studies we sought to conduct a candidate gene association approach to investigate common variants in the PPARG gene with SSc.
Despite the preliminary nature of our findings and the need for further studies in order to validate the QTL effects found in our study before being effectively able to conduct a candidate gene approach, it is worth commenting on the genes that may underlie the most relevant QTL effects described here.
The aim of this study was to conduct a candidate gene association study using the FI as a phenotypic measure in 3,160 community-dwelling individuals over the age of 50 in the English Longitudinal Study of Ageing (ELSA) panel study.
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Accordingly, we conducted a "candidate screen" to identify additional loci involved in the gene silencing associated with TPE.
Since, prior to this study, only five genes have been identified that are Su TPE s, we conducted a candidate screen for Su TPE) in Drosophila by testing point mutations in, and deficiencies for, proteins involved in chromatin metabolism.
To address this we conducted a candidate gene association study using the Frailty Index in the ELSA.
We conducted a candidate gene association study to confirm the association result using 147 BD patients and 951 controls.
Based on knowledge from the animal studies, we conducted a candidate association study in a human case-control study of RA.
We, therefore, conducted a candidate association to investigate the association between the identified risk genes/loci and BD in the non-Turkish ethnic population.
As tamoxifen-induced reductions in percent mammographic density (PMD) have been linked to the risk and prognosis of breast cancer, we conducted a candidate gene study to investigate the association between germline CYP2D6 polymorphisms and PMD change.
However, a statement about a political position "can go beyond being a statement about his political position and become a statement about the personal character or conduct of a candidate" (para 114).
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