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In addition to preventing further degenerative changes, IL-1ra microspheres may foster a microenvironment that is anti-inflammatory and more conducive to stem cell survival, differentiation and biosynthesis [17].
A microenvironment that is conducive to stem cell self-renewal is referred to as a stem cell niche [ 16, 68].
Given the expected range of diffusion of these sorts of molecules (on the scale of 10 to 100 μm), it quickly becomes apparent that the environment most conducive to stem cell maintenance should exist at the interface between epithelium and stroma, a result that is supported by mathematical modeling [ 76].
If this is the case, then the niche might best be thought of not simply as an environment conducive to stem cell functioning, but as an apparatus for communicating information about the state of a tissue back to the stem cells that maintain it.
Similar(56)
To stem redemptions.
Root canal disinfection and the establishment of an intracanal microenvironment conducive to the proliferation/differentiation of stem cells play a significant role in regenerative endodontics.
Hard power failed to work in Afghanistan and Iraq, and with respect to stemming the tide of Daesh through air strikes, and the West is forced to apply 'soft' pressure in an environment not conducive to being effective.
They also displayed a controlled release of dexamethasone over a period of time conducive to tissue regeneration and allowed human mesenchymal stem cells to adhere to and proliferate on them in vitro.
Small internal loops in the stem are tolerated, but the presence of large internal loops, protruding stem loops, or short stems do not appear be to conducive to high frequency translocation.
Sh-1 produced little RNA of the expected size(21-23 nt), perhaps because the stem-loop structure was ntt conducive to operhapsprocessing.
Leaves are supported by the stem and are oriented in a manner conducive to maximizing the amount of leaf area involved in trapping sunlight for use in photosynthesis.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com