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Most important, we noted that in the non-tumor-bearing arthritic mice (SKG and CII-injected C57BL/6 mice), the number of MCs was increased compared with nonarthritic tumor-bearing Balb/C or PyV MT mice, indicating that the arthritic milieu by itself can increase the MC population in the bones and lungs, creating a conducive niche that attracts the SCF-expressing tumor cells.
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Nevertheless, the inefficiency of metastasis formation observed in experimental animals (e.g., [ 18]) probably suggests that even the most conducive endogenous niche microenvironments are sparsely distributed in organs where metastases develop.
This outcome is typical of compensatory regeneration at early stages of disease progression and likely reflects the action of cues from a regeneration-conducive SC niche that resolve FAP bipotency into the pro-myogenic phenotype.
Accessory chromosomes may provide a special type of "genome niche", conducive for rapid adaptive evolution of virulence-related genes, perhaps due to fewer selective constraints on sequence evolution [ 15].
Interestingly, biochemical studies have revealed that POSTN supports the incorporation of TNC onto ECM fibrils within the ECM architecture, suggesting that the interactions of these matricellular proteins in the ECM may form the basis of a niche that might be conducive for metastasis (Kii et al, 2010).
A microenvironment that is conducive to stem cell self-renewal is referred to as a stem cell niche [ 16, 68].
If this is the case, then the niche might best be thought of not simply as an environment conducive to stem cell functioning, but as an apparatus for communicating information about the state of a tissue back to the stem cells that maintain it.
These cells take residence within the target organ and are thought to establish a 'pre-metastatic niche', a term used to describe a set of novel microenvironmental stimuli that are conducive for tumor cell survival and growth [ 91].
It's unclear why Young would need a pseudonym, but the vagueness of his identity has likely been conducive to building his poetry-world persona, a persona that's both marketable and disproportionately influential in this niche genre.
Niche World".
Noise level: Conducive to conversation.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com