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Efficacy has been defined as the extent to which a specific intervention, procedure, regimen, or service produces a beneficial result under ideally controlled conditions when administered or monitored by experts.
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Nicotine significantly increased lever pressing and the number of earned reinforcements on both levers in the two choice conditions and when administered s.c. compared to all groups that did not receive nicotine.
Because acquisition of conditioned taste avoidance is strengthened when an agent that is capable of inducing avoidance is administered after LiCl injection, it was determined in experiment 1 that a 6 μg/kg dose of vasopressin did not induce conditioned taste avoidance when administered 50 min after consumption of a sucrose solution.
Additionally, 5-HT1B receptor knockout mice do not display cocaine-conditioned place preference (CPP), whereas in rats 5-HT1B receptor agonists enhance cocaine-CPP but produce conditioned place aversion when administered alone.
Furthermore, a transgenic rice seed-based vaccine expressing cholera toxin B subunit was resistant to the harsh environmental conditions of the gastrointestinal tract when administered orally and maintained immunogenicity as a result of its accumulation in stable PBs [ 81].
Two reports found that remifentanil boluses of 0.25 and 0.50 μg.kg−1 improved LMA-Classic™ insertion conditions while maintaining haemodynamic stability when administered concurrently with propofol; however, remifentanil at 0.5 μg.kg−1 resulted in significant haemodynamic disturbances [ 24, 25].
"When administered under supportive conditions," the paper concluded, "psilocybin occasioned experiences similar to spontaneously occurring mystical experiences".
In the present microdialysis experiments, the reactive oxygen species H2O2 strongly increased hypoosmotic levels of glutamate and aspartate, but had little effect when administered under isoosmotic conditions.
These data were paralleled by the effects of GPER interference and G15, AG, U0126, and WM on cell viability when administered under identical conditions (Fig. 5B).
When administered under hyperglycemic conditions, NT stimulates migration but inhibits the proinflammatory status of macrophages thus contributing to the resolution of inflammation and allowing the progression to the migration-remodeling phases of wound healing.
Researchers have discovered that a cocktail of other bacteria isolated from Caribbean reef tracts, when administered under laboratory conditions, helped prevent white pox disease progression in the polyp Aiptasia pallida, a coral cousin and surrogate model for coral research.
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