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Whole-cell current traces were evoked every 5 s by a 100-ms depolarization to the voltage corresponding to the maximal activation of the NaV-subtype in control conditions, starting from a holding potential of −90 mV.

The goal of this work is to provide a robust tool in both extreme and tolerable overtopping conditions, starting from the ANN recently developed by the authors for wave reflection, overtopping and transmission.

Most of the studies and applications conducted so far used statistical or heuristic techniques to predict traffic conditions starting from historical and real-time traffic data collected by fixed sensor networks.

In this paper we work in the framework of the approximate method proposed in [12, 13], in which the expansions of the dependent variable are introduced also in the Lie group transformations so that one obtains an approximate Lie operator which permits to solve in hierarchy the invariance conditions starting from the classification of unperturbed equation (3).

Furthermore, different ranges of oxygen levels have been considered as hypoxic conditions, starting from almost anoxic conditions of 0.1% up to 2% O2, oxygen levels in the body vary from around 16% in the pulmonary alveoli down to approximately 6% in other tissues [37].

Figure  3A shows that both 1 μM Sunitinib and 1 μM Sorafenib significantly decrease cell migration of about 15-20% compared to control conditions starting from 4 to 6 hours after treatment in all of the three lines.

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Hence, all the curves for different base conditions start from unity.

Aiming designing molecular distillators with industrial dimensions starting from the simulation of a reduced one or even establishing an operating condition starting from a smaller equipment, a methodology was developed looking for an easy and fast form for scaling-up.

We chose contrasted culture media to reflect a wide range of possible environmental conditions, starting with 0.25% glucose because from this concentration the maximal expression of glycolytic genes is achieved [52].

The presented synthetic route requires mild conditions, starts from low-cost substrates and leads to the formation of the target products with good yields.

The present prototype has been designed to operate under room conditions and starting from springtime 2009 a Grant with F4E is in progress for the design and the assessment of the IVVS system for ITER, keeping in account all the environmental conditions and constraints.

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