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Further, under conditions of damage, reactive astrocytes within the cortex are reported to express Shh and induce oligodendrocytic progenitor proliferation (68).
Therefore, our results uncover the presence of a 'regeneration-specific Wg niche', which is regulated and required for ISC proliferation in conditions of damage or stress.
Below we describe in more detail how this system responds to changes in homeostatic balances under various conditions of damage and repair.
Typically, in conditions of damage of one part of the brain, other parts of brain or another hemisphere (right in this case) compensate and repair morphofunctional balance of the CNS.
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Five damage states were defined to express the condition of damage.
Four damage states: slight, moderate, major, and collapse were defined to express the condition of damage.
Under conditions of DNA damage, RecA proteins recognize this damage by polymerizing on stalled single stranded DNA (ssDNA).
Background: Rosemary (Rosmarinus offcinsalis L) has a liver protection function under various conditions of liver damage.
Y family polymerases must be tightly regulated to prevent aberrant mutations on undamaged DNA while permitting replication only under conditions of DNA damage.
The loss of responsiveness to inhibition of the Notch pathway in the first postnatal week is due in part to a down-regulation of Notch receptors and ligands, and we show that this down-regulation persists in the adult animal, even under conditions of noise damage.
Degradation of ubiquitinated p53 disrupts p53-mediated tumour suppression under conditions of DNA damage and oncogenic stress.
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