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Paleoenvironmental reconstructions using bulk geochemistry indicate warm and wet conditions during development of the Ngira paleosol that probably supported a tropical seasonal forest on a stable upland surface for 10s to 100s of thousands of years.
Here, we manipulated environmental conditions during development (small vs. large brood size, and hence sibling competition) and in adulthood (easy vs. hard foraging conditions) in a full factorial design in zebra finches, and studied effects on baseline (Bas-CORT) and stress-induced (SI-CORT) corticosterone in adulthood.
These body mass losses were the stronger the earlier subjects had experienced poor nutritional conditions during development.
The earlier subjects experienced poorer nutritional conditions during development, the higher their relative body mass loss was (Fig. 1b).
These distinct features of the duplicated IGFBP-1 genes could allow greater flexibility and fine-tuning of IGF actions under various physiological conditions during development.
Recent evidence suggests that phenotypic plasticity in bill morphology can occur in response to poor conditions during development.
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This condition can now be effectively treated through the use of fetal laparoscopic procedures, but the potential for lifelong morbidity related to this condition during development is apparent.
This raises the question of the specific time point and conditions during growth and development when either of these opposing mechanisms could dominate and how signalling is mediated to trigger the expression of one mechanism or the other.
The model is based on the assumption that, under physiological conditions during normal development where growth factors are present in limiting concentrations, two classes of signals are required to generate sufficient numbers of activated integrins.
Met-regulated invasive growth plays important roles under physiological conditions - during development and tissue regeneration - and controls cancer invasion and metastasis [ 3, 5].
As conditions change during development or in an adult tissue, energy needs will change.
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CEO of Professional Science Editing for Scientists @ prosciediting.com