Sassetti, C. M., Boyd, D. H. & Rubin, E. J. Comprehensive identification of conditionally essential genes in mycobacteria.
Background: Arginine is a conditionally essential amino-acid with immuno-modulatory properties, mainly through the nitric oxide (NO) pathway.
The suggestion that glutamine (Gln) might become conditionally essential postpartum in dairy cows has been examined through increased postruminal supply of Gln.
In this chapter, we explore the rationale behind understanding this molecular landscape, with particular attention to essential inputs, conditionally essential inputs, and nonessential inputs.
Carnitine is a conditionally essential amino acid-like compound involved in the transport of long-chain fatty acids into the mitochondria during the β-oxidation process.
Watermelon is a rich source of citrulline, an amino acid that can be metabolized to arginine, a conditionally essential amino acid for humans.
The supplement comprised a mixture of essential (l-threonine) and conditionally essential (l-glutamine) amino acids, polar lipids, oat bran rich in beta glucans and yeast extract.
To explore the possibility that one of these homologs, Rv3711c, participates in an unknown redundant pathway, we used transposon capture and sequence (TraCS) to identify genes conditionally essential in an Rv3711c deletion mutant.
l-Arginine (l-Arg) is a conditionally essential amino acid for humans, which is the substrate for both arginase (ARG) and the inducible form of nitric oxide synthase (iNOS) enzymes.
For example, in silico knock-out mutant studies and comparative analysis have provided the conditionally essential gene sets and corresponding functional modules under various growth conditions in E. coli and S. cerevisiae (Segre et al. 2005; Joyce et al. 2006).
Others may be conditionally essential for certain ages or medical conditions.
