Validation of Alu Exon Changes Using RT-PCR, Related to Figure 3 and Data S1 (A and B) Validation of Alu exons that were called as differentially regulated using DEXSeq and conditional thresholding (A, Data S1A) or that are more than 2-fold upregulated in the RNA-seq data (B, Data S1B).
But adding a third regulator to the cluster that does not regulate that target (conditional below threshold) reduces the contribution to the score to 2/3.
As we're trying to find a deterministic Boolean network, we've binarized the gene expression based on a conditional probability threshold of 0.5.
This means setting the posterior class-conditional probability threshold (P t ) equal to 0.5, that is, x is assigned to class M if P(M | x ) is greater than 0.5 and otherwise to class N.
Second, in HVD modeling the log-normal expression for risk as a function of applied dose (Expression 1) is best interpreted as the conditional distribution of threshold doses given that the threshold is positive (i.e., as extra risk).
Posterior probability maps denote the probability that the connectivity value exceeds a chosen threshold, conditional upon the noisy observations.
These curves represent the probability of exceeding a given structural damage state (or performance threshold), conditional on the mean wind speed.
It is important to note that whereas the computation of net effects requires statistically significant unconditional and conditional effects, a threshold may be apparent even when only the conditional effect is significant.
Another advantage of using such conditional probability and threshold is that it takes into account the seasonality of flu.
