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The values of design sciences are not criteria for the acceptance of theories or models, but rather antecedents of conditional recommendations of actions.
Conditional recommendations were made primarily because of reservations on implementation issues, as well as low quality of the evidence.
These factors limited the use of the GRADE approach in developing recommendations, and our frequent use of conditional recommendations reflects uncertainty associated with current evidence base for diagnosis.
Similar(57)
WHO has recommended use of pyrazinamide (conditional recommendation, very low-quality evidence) without pyrazinamide susceptibility testing, which is technically difficult and often not performed.
Pirfenidone and nintedanib were approved for treatment of IPF in 2014, but they received only a conditional recommendation for use and, thus, to date no drugs are strongly recommended for IPF.
ATLANTA — The byzantine, often inscrutable negotiations toward a new N.F.L. labor agreement took another surprising turn on Wednesday when players, with a draft of the settlement in their hands in Washington, gave only a conditional recommendation for approval contingent on the negotiation of a few final terms, according to two people involved in the players' actions.
A "moderate," "weak," or "very weak" level of proof resulted in a "conditional" recommendation ("should probably be done", "should probably not be done…").
(Conditional recommendation, very low quality of evidence).
(Conditional recommendation acknowledging major resource implications)" (WHO Rapid Implementation 2011).
(Conditional recommendation, low to very low quality of evidence).
In fact, the WHO 2014 guidelines only make a conditional recommendation for testing and treatment in this group.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com