Sentence examples for conditional over from inspiring English sources

Clearly, additional mouse models, especially those with conditional over expression of Trim24, and manipulation of diet, along with mechanistic studies of functional domains and intersecting pathways, are needed to determine how epigenetic variables and tissue-specificity dictate metabolic reprogramming by TRIM24.

Dyle may have taken the lead in conditional over-the-air broadcasting, cobbling together about 60 Fox, NBC and Univision stations.

In this study, to ascertain the correlation between the development of the PCD-like phenomenon and the expression of TAO in T. brucei, we genetically engineered T. brucei for conditional over-expression of the TAO gene.

Conditional over-expression of the hydrogen peroxide-producing enzyme superoxide dismutase (SOD) also increased fly activity and altered the patterns of locomotor activity across days and weeks.

We have previously shown that in C2C12 cells, in which an inducible expression system allows conditional over-expression of RNase L (C2-RNase L cells) by addition of Isopropyl-β-D-thiogalactopyranoside (IPTG) in the culture medium [20], MyoD was down-regulated and myogenesis inhibited.

For example, conditional over-expression of tra during development significantly inhibited sexual differentiation in males, yet produced no significant change in adult life span.

Conditional over-expression of transformer female isoform (traF) during development produced male adults with inhibited sexual differentiation, however this caused no significant change in life span.

On the other hand, conditional over-expression of TGF- β1 in secretory cells (mammary and salivary gland epithelial cells) resulted in hyposalivation due to salivary gland fibrosis and atrophy [ 21].

Whole-mount ISH was performed on COET; Mesp1 Cre/+ embryos at E9.5; the COET (for Conditional Over-Expression of Tbx1) transgene expresses Tbx1 mRNA in response to Cre recombination (10).

Here conditional over-expression of both wild-type and mutant p53 transgenes indicated that, in adult flies, p53 limits life span in females but favors life span in males.

Thus, conditional over-expression of this cluster of seven miRNAs (miR-17-5p, miR-17-3p, miR-19a, miR-20a, miR-19b, miR-19b and miR-92) at the DN1 stage resulted in auto-immunity that was characterised by enhanced T-cell proliferation and survival, particular effector CD4+ T-cells.