Sentence examples similar to conditional on alignment from inspiring English sources
THESEUS functions in two modes: (i) one mode for superpositioning structures with identical sequences [such as different (NMR) models] and (ii) an 'alignment mode,' which superpositions structures with different sequences (i.e. with missing data) conditional on a known alignment.
Like most codon modeling approaches, PhyloCSF assumes statistical independence of each codon site from all the others in the alignment (conditional on the model parameters).
Thus it becomes desirable to propose and investigate more efficient multiple-imputation-like approaches such as using posterior ancestor samples which may offer multiple representative alignment results conditional on a reference species sequences for sequence set probability elicitation.
The choice will depend on alignment.
We propose Monte Carlo integration algorithms to sample the unknown ancestral and/or root sequences a posteriori conditional on a reference sequence and apply pairwise Needleman Wunsch alignment between the sampled and nonreference species sequences to estimate the probability.
As the question under consideration concerns the divergence of specific genes and proteins over a (presumably) long time scale, the capacity to generate reasonable alignments diminishes with increasing time of divergence between types, conditional on the rate of substitution.
SIFT calculates the probability that an amino acid at a position is tolerated conditional on the most frequent amino acid being tolerated by interrogating the amino acids appearing at each position in the alignment.
But it cannot be conditional on fantasy.
Made the outlook conditional on inflation.
"Everything is conditional on his departure".
