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Researchers at Hebrew University in Jerusalem and the Israeli Defense Force's Medical Corps have found that a variety of chemicals penetrate the mouse blood-brain barrier much more readily when the mice are forced to tread water, a condition that induces stress.
We aimed at establishing and validating an EPS condition that induces a gene expression pattern resembling that of a trained muscle.
We tested N2 for its response to pathogens at 27°C (a condition that induces ∼5 10% dauer larvae on OP50) to ensure the effect we observed was not unique to Daf-c mutants [11].
This result confirmed a previous study showing that the specific activity of ribonucleotide reductase was increased in dnaB and dnaE mutants at the non-permissive temperature (a condition that induces the SOS system in these mutants) or in wildtype cells challenged with either nalidixic acid or bleomycin [35].
The systematic approach with defined statistical criteria means that this method can theoretically be used not only to identify candidates of the drug targets but also to assess the effects of any condition that induces morphologic changes (e.g., genetic mutations, nutritional starvation, and temperature shifts, among others).
In a study by Cathelyn et al., bacteria were grown at 26°C in BHI medium, while in this study, bacteria were grown at 37°C in chemically-defined TMH medium without calcium, which is a condition that induces the expression of the T3SS and many other virulence factors required for successful infection of mammals.
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It's a condition that encourages contemplation.
Graves' disease, an overactive thyroid condition that speeds up metabolism.
Kovaleski has arthrogryposis, a congenital condition that affects joint movement.
"It's a condition that is often misdiagnosed and overdiagnosed.
It is a universal condition, that of vulnerability.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com