Collaborative care significantly reduced the HbA1c level compared with control conditions (pooled WMD was −0.33% (95% CI −0.66%too −0.00%)).
Collaborative care significantly improved standardised depression outcomes compared with control conditions (pooled SMD was −0.32 (95% CI −0.53 to −0.11)).
Two-way random average measures, ICC 2,k), in all conditions pooled were 0.79 CI 95% [0.70-0.86] for onset angle, and 0.85 CI 95% [0.79-0.86] for cessation angle.
Testosterone therapies consistently failed to show better standardised HRQoL outcomes compared with control conditions (pooled SMD was –0.03 (−0.32 to 0.25); I=0%, p=0.934).
The liver tissue was harvested from 6 7 embryos under sterile conditions, pooled, minced and washed subsequently with phosphate-buffered saline (PBS) supplemented with 1 mg/ml glucose.
Testosterone therapies consistently failed to show significant improvements in standardised peak VO2 outcomes compared with control conditions (pooled SMD was 0.21 (−0.15 to 0.56); I=4.8%, p=0.379).
Nonetheless, sample sizes from other sites, or for specific conditions pooled over multiple sites were still larger than most recent studies of ED visits, and pooled estimates were generally similar, although less precise, when Edmonton was excluded.
For the selected conditions, pooled unadjusted mean physical component summary scores were: 44.4 for hypertension, 38.9 for ischaemic heart disease, 35.9 for heart failure, 39.5 for lower back pain, 36.0 for osteoarthritis and 36.5 for rheumatoid arthritis.
Testosterone therapies significantly improved standardised peak muscle strength outcomes compared with control conditions (pooled SMD was 0.31 (0.05 to 0.56)), and there was little evidence of statistical heterogeneity between studies (I=0%, p=0.839).
For each condition, pools were obtained by combining equal amounts of total RNA from five different experiments.
