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The "complex geriatric syndrome" is significantly related to a condition of "frailty" that is, in turn, related to age.
Once the condition of frailty is reached, cells are prone to age-related physiological decline (Kirkland & Peterson, 2009).
The complex condition of frailty continues to gain increased attention in the search to improve healthy life expectancies for aging populations and healthcare for older people.
As regards to this aspect, several conditions are known to modify plasma lipids in the elderly including age itself, gender, apoprotein E phenotype [ 17], impaired functional status [ 18], a condition of "frailty" [ 19], and an inflammation state [ 20].
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This ensures that the agent is not acting as a rational agent, which is similar to the condition of human frailty that is influenced by desires and temptations and makes them take risks.
Additionally, while chronological age is an independent risk factor for adverse outcomes in many conditions, the assessment of frailty in elderly patients may be a superior predictor of outcomes than chronological age in this patient population [ 17].
The collective process of aging and the presence of concurrent health conditions are associated with functional status impairment and subsequently a determinant of frailty, a condition becoming increasingly important to consider among adults aging with HIV [ 63].
38 39 The phenotypic approach defines frailty on the basis of several items, such as weight loss, exhaustion, weakness, slowness, or low physical activity, and considers any three conditions as an indication of frailty.
One possible explanation for this increase is that the clinical condition and frailty of clients tends to worsen so that if they are admitted they stay for longer.
For the diabetic elders with unintentional body weight (BW) loss, sarcopenia, or sarcopenic obesity, the focus should be on avoiding medications with overt gastrointestinal side effects, which may aggravate the condition of malnutrition, worsening the frailty status.
Those whose actions are conditioned by an exquisite sense of frailty, by an understanding that it's more important to avoid the worst than to attain the best, may better serve those ideals in the end.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com