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Moreover, the term 'appropriate condition' needs further explanation.
Behnam said it is fairly easy for a doctor to determine by reviewing the initial photograph and responses to a questionnaire whether a condition needs further investigation.
The role of inflammation, blood brain barrier disruption and oxidative stress in this condition needs further research.
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The mechanisms responsible for the NZB/W MCs being obviously hyperreactive in producing the two chemokines (OPN and MCP-1) under the baseline condition need further investigation, although we thought that the complicated genetic defect of lupus-prone mice could be one of the potential mechanisms responsible for this particular property.
However, the molecular mechanism of this dedifferentiation phenomenon under hypoxic conditions needs further study, and we speculate that SOX-2, OCT-4, KLF-4, Nanog and Lin-28A may have an important role in this process, based on traditional studies regarding the formation of iPS cells by these defined factors and the influences of these factors on tumors.
However, data base on the ionospheric structuring and key driving parameters, such as perturbation electric fields and winds (under disturbed and quiet conditions) needs further enrichment and improvement (from satellite and ground-based observations) for making continuing progress toward achieving better predictive capability on the ionospheric weather.
While the transgenic Camelina sativa produced a higher seed yield under controlled environmental conditions, whether the transgenic lines could perform well under field conditions needs further experiments.
Therefore, the actual mechanisms underlying memory decline in these two conditions need further investigation.
Persons with medical or eye conditions needing further assessment and treatment were referred to the nearest healthcare facility.
Since chronic exposure to glucose metabolites, as encountered in diabetes, induces adverse effects, the proper roles of these metabolites during acute conditions need further elucidation.
While the later one is not associated with safety hazards of the scanning itself, the potential discovery of pathological conditions needing further investigation or the need to obtain an informed consent, have to be considered as critical limitations [ 1].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com