Sentence examples for condensed configuration from inspiring English sources

The mitochondria in cancer cells, independently of histogenesis, predominantly are seen with lucent-swelling matrix associated with disarrangement and distortion of cristae and partial or total cristolysis and with condensed configuration in minor scale.

There are two major classes of viruses based on the protein capsid: (1) those in which a single (or segmented) linear nucleic acid molecule with two free ends is essentially completely extended or somewhat coiled (a helix) and (2) those in which the nucleic acid, which may or may not be a covalently closed circle, is wound tightly into a condensed configuration, like a ball of yarn.

An extreme of the condensed configuration is the ultracondensed configuration (Fig. 4C).

We observed a similar morphology in IPSC and ESC mitochondria that we interpreted more as a "condensed" configuration than underdevelopment; however, both properties might contribute to the morphological appearance.

Quantification of mitochondrial configuration in each cell line was performed by manual counting of mitochondria of orthodox or condensed configuration in 4 6 representative EM images (of each line) by six unbiased volunteers unfamiliar with the study.

Figure 4B, on the other hand, shows a mitochondrial morphology referred to as the condensed configuration, and is characterized by mitochondria with a dark, condensed matrix and thus expanded, translucent cristae.

As suggested by the representative images of Fig. 4D K, the FIB, IPS, and ESC lines displayed mitochondrial complements composed predominantly of mitochondria in a condensed configuration, whereas TER cells lines displayed an overwhelming preponderance of mitochondria in an orthodox configuration (Fig. 4L).

The complexity of cristae in mitochondria of the condensed configuration is manifest using a 3D technique such as ET. There are generally fewer and larger cristae in the condensed organelle, as displayed in the reconstructions in the lower panel of Fig. 4B, indicating that cristae remodeling needs to occur upon transition from the orthodox to the condensed conformation.

A decondensed ('open') configuration allows DNA binding proteins such as transcription factors access to binding sites, whereas a condensed ('closed') configuration blocks transcription binding sites, thereby regulating gene transcription [24].

Transcriptionally inactive chromatin is typically characterized by a condensed, nonpermissive configuration, inaccessible to transcription factors.

This study examines these effects by numerically modelling the condenser at the system level and using the results to build a mathematical model to predict the optimal condenser configuration.