The reduced overall surface area of a short oligonucleotide also results in a lower local concentration of condensing bodies; for DNA, these may be ions or DNA-binding proteins that form a local region of high concentration simply by their affinity for DNA (and in the case of proteins, irrespective of sequence).
Fragmented, but equally condensed, apoptotic bodies were also present.
Theo Colborn, president of TEDX, first conceptualized condensing the body of EDC literature into a user-friendly graphic format.
In contrast, after treatment with NB7M (2 μ M) only ∼20% of cells appeared unaffected, whereas the majority of cells showed densely stained nuclear granular bodies of highly condensed chromatin ('apoptotic bodies'), a classic hallmark of apoptosis (Earnshaw, 1995).
The X and Y chromosomes typically join at their pseudoautosomal regions to form a highly condensed and inactive XY body during the pachytene stage of meiosis (Fig. 1A).
He then established an analogy between paramagnetic bodies and perfect gases and, as a result of this, between ferromagnetic bodies and condensed fluids.
When treated with 4c at a higher concentration of 5.0 μM, the nuclei of many more cells were highly condensed and the apoptotic bodies were pervasive in the visual field (Fig. 4c).
Macrophages exposed to preparations of clones containing the B. pseudomallei hemagglutinin-like gene display a very interesting phenotype with formation of dramatic actin projections or 'tails' extending towards neighboring cells from shrunken cell bodies containing condensed nuclei.
We next asked whether UBXN2A expression leads to apoptotic characteristics (condensed chromatin and apoptotic bodies), which are ubiquitous aspect of apoptosis.
Electron microscopic analysis of glioma cells co-infected with Adv-p53, Adv-APAF1 and Adv-Casp9, revealed apoptotic bodies and condensed chromatin in the nuclei 3 days after infection.
