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Whole brain weights were reduced only in the PND 6 8 group concurrently with the reduction of GDNF mRNA in cortex in this group.
Thus, we suggest that the crystallization of Fe2TiO5 and Fe2Ti2O7 phases concurrently with the reduction of iron (III) to iron (II) ions by the formed carbon-, chlorine- and even nitrogen-contained species, in the case of urea-doped films, occurred during thermal treatment [25, 26].
ThT assay of samples containing Aβ and heat-treated Hsp27, however, showed that Hsp27-mediated suppression of Aβ aggregation disappeared concurrently with the reduction of amyloid oligomer conformation resulting from the heat treatment (Figure 3C).
c-Myc levels (orange line) tracked nearly concurrently with the reduction of Ikaros levels.
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Horseradish peroxidase-linked anti-DIG (anti-DIG-HRP) was employed as the electrochemical label, which could concurrently catalyse the oxidation of 3,3′,5,5′-tetramethylbenzidine 3,3′,5,5′-tetramethylbenzidineO2 TMByield an electron transfer to the electrode surface for electrochemical transduction of DNA hybridisation event.
An integrity check is performed concurrently with the reduction process to avoid truncated chemical paths and mass accumulation in intermediate species.
Previously we observed that BRB inhibited mTOR/S6 signaling concurrently with reduction of the level of endogenous oxidants and constitutive DNA damage response.
T-lymphocyte subpopulations could be restored partially by entecavir treatment in patients with chronic hepatitis B concurrently with reduction of viremia.
Taken together with recent reports of previous studies [ 11- 13, 28- 31], all this accumulating evidence that efficient antiviral T cell response can be restored by mono-antiviral treatment in CHB patients concurrently with reduction of viremia demonstrates the importance of viral load in the pathegenesis of T cell failure in chronic HBV infection.
An efficient antiviral T cell response can be restored transiently by lamivudine treatment in patients with chronic hepatitis B (CHB) concurrently with reduction of viremia.
Our observation that the gero-suppressive agents inhibit constitutive level of mTOR activation concurrently with reduction of DNA damage signaling [ 33] provides evidence of a direct linkage between mTOR activation and oxidative DNA damage (Fig. 7).
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